Biology & Marine Biology

Faculty & Staff

 

warner.jpg

Jacob F. Warner, Assistant Professor

Ph.D., Genetics and Genomics, Duke University, Durham, NC, 2013
B.S., High Point University, High Point, NC, 2006
Myrtle Grove 2331 | Center for Marine Science,
5600 Marvin K. Moss Lane, Wilmington, NC 28409-5928
warnerj@uncw.edu | http://warnerlab.org

Research Interests:  

Our lab uses marine invertebrates to study how organisms develop from a single cell to an embryo. We’re particularly interested in how genes are arranged into regulatory networks to effect cell fate decisions and morphological changes in the early embryo. We study this by using molecular and comparative genomic approaches with a variety of model systems including sea urchins and sea anemones.

Selected publications

Warner JF, Guerlais V, Amiel AR, Honston H, Nedoncelle K, Rottinger ER (2018) NvERTx: A gene expression database to compare Embryogenesis and Regeneration in the sea anemone Nematostella vectensis. Development. 2018 May 17;145(10).

Warner JF, Miranda EL, McClay DR (2016) Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin. Developmental Biology 411(2):314-24.

Amiel AR, Johnston HT, Nedoncelle K, Warner JF, Ferreira S, Röttinger E (2015) Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis. International Journal of Molecular Sciences 16(12):28449-71.

Warner JF, McClay DR (2014) Left-right asymmetry in the sea urchin. Genesis 52(6):481-487

Warner JF, McCarthy AM, Morris RL, McClay DR (2014) Hedgehog signaling requires motile cilia in the sea urchin. Molecular Biology and Evolution 31(1):18-22.

Warner JF, McClay DR (2014) Perturbations to the hedgehog pathway in sea urchin embryos. Methods in Molecular Biology 1128:211-21.

Warner JF, Lyons DC, McClay DR (2012) Left-right asymmetry in the sea urchin embryo: BMP and the asymmetrical origins of the adult. Plos Biology 10(10):e1001404.

Walton KD, Warner JF, Hertzler PH, McClay DR (2009) Hedgehog signaling patterns mesoderm in the sea urchin. Developmental Biology 331(1):26-37.