Organic
Development of new methods for organocatalytic alpha-amination of aldehydes.
Diversity-oriented synthesis of alkaloid-inspired compound collections for medicinal applications.
Exploration of the properties and reactivity of strained organosilanes.
New transition metal-catalyzed and organocatalytic methods for the synthesis of chiral, non-racemic organic molecules.
Catalyst development and study of reaction mechanism.
Application in bioactive natural product total synthesis.
Isolation, synthesis, and structure elucidation of bioactive marine lipids.
Synthesis and NMR characterization of bioactive heterocycles.
Microbial natural products drug discovery
Natural products structure elucidation
Mass spectrometry-based bioassay development for drug discovery
Mass spectometry-based environmental metabolomics
Organic synthesis of DNA-alkylating molecules.
Design, organic synthesis, and investigation of molecules that target specific receptors on cells.
Targeting specific cell-types with DNA-damaging agents that induce cell-death, but not mutations, for potential therapeutic applications in diseases such as cancer and diabetes.
Application of novel screening technologies for marine natural products drug discovery
Structure determination of marine and terrestrial natural products
Application and method development in NMR spectroscopy
Online organic reaction and bioprocess monitoring & mechanistic studies
Chemical ecological studies in the context of drug-discovery
