Sarah Fausett

I am a cell physiologist and molecular biologist with 20+ years experience. My research program focuses on the cellular and genetic mechanisms that underlie aging and age-related disease and how these processes simultaneously affect growth and reproductive processes. My work often revolves around energy and protein homeostasis--two fundamental physical challenges for cells. To study these processes I use the tiny nematode model organism, C. elegans, which is an excellent model organism for the study of both reproduction and aging. I also have deep pedagogical training. As an instructor, I have taught Human Anatomy and Physiology for over 20 years and regularly mentor undergraduate and graduate as they complete research projects in my lab.

Education

B.S. in Biology, Central Michigan University
PhD. in Cell Biology Duke University

Specialization in Teaching

While at Duke University, I received training in pedagogy and earned a Certificate in College Teaching. Soon after I began my teaching career at Durham Technical Community College. I now have over 10 years experience teaching Human Anatomy and Physiology.

Research Interests

Though separated from us by at least 600 million years of evolution, Caenorhabditis nematodes use a remarkably conserved tool-kit of genes to navigate the challenges and dangers of being alive on planet Earth. Oxidative stress, UV light, and excessive heat represent only a few of the miseries that plague our cells, leading to disease, aging, and death. Like us, these little worms walk a tightrope of energetic trade-offs to combat this onslaught of stressors as they mature and reproduce, securing the immortality of their genes. In the ETIRA lab, we use the elegant simplicity of nematodes to probe the genetics and physiology of energetic trade-offs in reproduction and aging, unlocking secrets of both evolutionary fitness and human disease.