Wilmington International Airport (ILM) offers non-stop flights to and from LGA, PHL, ATL, CLT, and DCA on Delta and US Airways. 

For additional choices in flights in non-stop flights, Myrtle Beach International Airport (MYR) is 1.5 hours from Wilmington and Raleigh-Durham International Airport (RDU) is 2 hours from Wilmington. 

By car, UNCW is accessible via I-40 and U.S. Highways 421, 17 and 74-76.  Campus maps are available here.